F surgery. POH and POPA had been shown to become independent predictors of post-operative length of remain. The existing study findings and literature documentation are constant together with the notion that POH, in aspect, may perhaps be a manifestation of occult- or micro-pulmonary aspiration during horizontal recumbency. Future studies may well showDunham et al. BMC Anesthesiology 2014, 14:43 http://biomedcentral/1471-2253/14/Page 9 ofthat modest reverse Trendelenburg positioning through basic anesthesia is associated with reduced POH and POPA rates.Abbreviations ASA: American society of anesthesiology; BMI: Physique mass index; EMR: Electronic medical record; ICU: Intensive care unit; PACU: Post anesthesia care unit; POH: Perioperative hypoxemia; POPA: Perioperative pulmonary aspiration. Competing interests The authors declared that they’ve no competing interests. Authors’ contributions CMD, BMH, AEH, EAC, and GSH conceptualized and made the study. CMD, BMH, and , EAC were involved in the day-to-day oversight of the study. CMD, BMH, and EAC performed the information collection. CMD performed the information evaluation. CMD, BMH, AEH, EAC, and GSH performed the information interpretation. CMD, BMH, EAC, and GSH performed the literature search and drafted the manuscript. CMD, BMH, AEH, EAC, and GSH critically revised the manuscript for significant intellectual content. All authors produced substantial contributions to conception and style, or acquisition of information, or analysis and interpretation of data. All authors have already been involved in drafting the manuscript or revising it critically for critical intellectual content material. All authors read and authorized the final manuscript. Authors’ data CMD has 35 years experience as a Trauma Surgeon and is a board SIRT2 Activator Purity & Documentation certified Surgical Intensivist and is often a board certified Common Surgeon. BMH and EAC are seasoned full-time analysis assistants for The Trauma and Orthopedics Analysis Division. AEH is usually a board certified Anesthesiologist along with the Chief of Anesthesiology. GSH can be a board certified Common Surgeon, a Trauma Surgeon, as well as a board certified Surgical Intensivist. Acknowledgements No external supply of funding was involved. The authors wish to thank Marina Hanes for copyediting the manuscript. Author particulars 1 Trauma/Critical Solutions, St. Elizabeth Well being Center, 1044 Belmont Avenue, Youngstown, OH 44501, USA. 2Department of Anesthesiology, St. Elizabeth Overall health Center, 1044 Belmont Avenue, Youngstown, OH 44501, USA. Received: 26 January 2014 Accepted: 5 June 2014 Published: 9 June 2014 References 1. Cotton BR, Smith G: The reduced oesophageal sphincter and anaesthesia. Br J Anaesth 1984, 56(1):376. two. Morgan M: Handle of intragastric pH and volume. Br J Anaesth 1984, 56(1):477. three. Tiret L, Desmonts JM, Hatton F, Vourc’h G: Complications connected with anaesthesia potential survey in France. Canadian Anaesthetists’ Society Journal 1986, 33(three Pt 1):33644. 4. Kozlow JH, Berenholtz SM, Garrett E, Dorman T, Pronovost PJ: Epidemiology and effect of aspiration pneumonia in patients undergoing surgery in Maryland, 1999000. Crit Care Med 2003, 31(7):1930937. 5. Kluger MT, Short TG: Aspiration in the course of anaesthesia: a NF-κB Inhibitor Purity & Documentation overview of 133 circumstances from the Australian anaesthetic incident monitoring study (AIMS). Anaesthesia 1999, 54(1):196. 6. Blitt CD, Gutman HL, Cohen DD, Weisman H, Dillon JB: “Silent” regurgitation and aspiration throughout basic anesthesia. Anesth Analg 1970, 49(5):70713. 7. Charuluxananan S, Punjasawadwong Y, Suraseranivongse S, Srisawasdi S, Kyoko.