igure 4). Most annotated genes inside the biological processes category were connected to the inflammatory Nav1.3 manufacturer response and cellular metabolism. DEGs in comparison group S_Z vs. S_B had been primarily connected with GO terms connected to stimulation, biological processes connected with lipid synthesis, and metabolism, which include the lipid/organic substance catabolic approach and the inflammatory/stimulus response. The majority of DEGs in comparison group K_Z vs. K_B have been linked to stimulationrelated biological processes, G-protein coupled receptor activity, signal transduction-related molecular functions, and cellular components (cytoskeletal part, membrane component, cytoplasm), for example the acute-phase response, G protein-coupled peptide receptor activity, and transmembrane transporter activity. The majority of DEGs in comparison group H_Z vs. H_B have been assigned with biological processes associated with stimulus, cellular processes, and cellular components, like cellular response to endogenous stimulus, damaging regulation of biological method, regulation of primary metabolic process, and constructive regulation of biological course of action. The majority of DEGs in comparison group M_Z vs. M_B were related to stimulus, immune procedure, cellular processes, signal transductionrelated molecular functions, and cellular elements, for instance response to abiotic stimulus,Animals 2021, 11,9 ofpositive regulation of neutrophil migration, cellular response to interleukin-1, constructive regulation of biological approach, and intracellular signal transduction. The majority of DEGs in comparison group J_Z vs. J_B have been connected with stimulus, immune approach, G protein-coupled peptide receptor activity, cellular course of action, and cellular components, for example cellular response to chemical stimulus, G protein-coupled receptor signaling pathway, cellular response to interleukin-1, neutrophil chemotaxis, optimistic regulation of cellular course of action, and cell migration. The majority of DEGs in comparison group Z_Z vs. Z_B have been linked to cell improvement, tissue development, cellular approach, and cellular components, like striated muscle tissue improvement, striated muscle cell improvement, muscle structure development, and cell differentiation. Additionally, the evaluation identified 9, 21, 25, five, 12, and 1 KEGG pathways that were drastically enriched in DEGs in comparison groups S_Z vs. S_B, K_Z vs. K_B, H_Z vs. H_B, M_Z vs. M_B, J_Z vs. J_B, and Z_Z vs. Z_B, respectively (Figure five). The substantially enriched pathways in DEGs from comparison group S_Z vs. S_B primarily included the complement and coagulation cascades and protein digestion and absorption (Figure 6). The pathways substantially enriched in DEGs from comparison group K_Z vs. K_B mainly integrated complement and coagulation cascades, IL-17 signaling pathway, and αvβ3 Formulation PI3K-Akt signaling pathway. The significantly enriched pathways in DEGs from comparison group H_Z vs. H_B primarily incorporated the complement and coagulation cascades, protein digestion and absorption, PI3K-Akt signaling pathway, MAPK signaling pathway, and NF-kappa B signaling pathway. The pathways that were drastically enriched inside the DEGs from comparison group M_Z vs. M_B mostly included protein digestion and absorption, IL17 signaling pathway, TNF signaling pathway, NF-kappa B signaling pathway, NODlike receptor signaling pathway, and HIF-1 signaling pathway. The pathways that have been considerably enriched in the DEGs from comparison group J_Z vs. J_B mainly integrated