Smolarity state of white matter top for the detection of increased
Smolarity state of white matter leading for the detection of elevated choline [68,73]. The function of lipid homeostasis is identified to have a correlation using the severity of brain trauma. Imaging mass spectrometry can also be applied to visualize the lipid dynamics and molecular modifications occurring within the injured brain. In a study by Mallah et al., lipid changes had been tracked by MALDI-MSI (matrix-assisted laser desorption/ionization mass spectrometry imaging) in rats exposed to controlled cortical brain injury and identified the lipid alterations occurring at injury web-sites and distant regions [74]. To understand the function of lipid alterations within the post-TBI inflammation and regeneration process, yet another study by Mallah et al. identified the new lipid markers named acylcarnitines at distinct time points soon after injury. The expression of acylcarnitine was -Irofulven Protocol downregulation of ChAT contributing towards the loss of cholinergic neurons and reduced ChAT protein [813]. The cholinergic neurotransmi.