Ia. Minerals 2021, 11, 1175. https://doi.org/10.3390/ min11111175 Academic Editor: Sytle M. Antao Received: two September 2021 Accepted: 19 October 2021 Published: 22 OctoberKeywords: platinum; nanoparticles; Olesoxime Mitochondrial Metabolism intense acidophiles; Fe(III)-reducing bacteria; Acidocella sp.; Acidiphilium sp.1. Introduction Metal nanoparticles (NPs) have recently gained escalating attention owing to their prospective for technological innovation in several sectors, such as power, catalysis, pharmaceuticals, optics, and photonics industries. The massive certain surface region of nano-sized materials allows minimization from the metal consumption though maximizing its effect. Among other metal NPs, Pt(0)NPs are of certain significance. Their possible is extensively explored in applications which include automobiles, fuel cells, petrochemicals, electronics, nanomedicine, optics, drug delivery, and antimicrobial, antioxidant, and anticancer agents [1,2]. Additionally, the production of “green” hydrogen is gaining increasing focus worldwide as an alternative clean energy to contribute for the decarbonization in the environment. “Green” hydrogen is made by means of the water electrolysis reaction, wherein Pt plays a important function as the reaction catalyst. Despite its significance and increasing demand, Pt is defined as a important raw material and its Ziritaxestat custom synthesis future provide is facing concerns. Conventionally, the production of metal NPs employs multi-step physical and chemical approaches utilizing a top-down (bulk metal is mechanically broken down to NPs) or bottom-up approach (precursor metal ions are assembled to create NPs) [1]. Nevertheless, the necessity to prevent toxic chemical substances and hazardous situations has led to an escalating interest in greener and simpler biological options. So far, the biological fabrication of metal NPs explored a range of life types, for instance bacteria, yeast, fungi, algae, and plants, for metal species such Au, Ag, Pd, Pt, Ni, Co, and Fe [3,4]. The size of biogenic metal NPs can be controlled by modifying circumstances for example concentrations of electron donors and reaction inhibitors [5,6].Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.Copyright: 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is definitely an open access article distributed below the terms and circumstances of your Inventive Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ four.0/).Minerals 2021, 11, 1175. https://doi.org/10.3390/minhttps://www.mdpi.com/journal/mineralsMinerals 2021, 11,two ofAmong those microorganisms or plants as the template for NPs’ production, a number of bacterial species possess the capacity to lower soluble metal species to zero-valent nanometal. For the bio-Pt(0)NPs’ production, various bacterial species have already been utilized so far, e.g., Acetobacter xylinum [7], Acinetobacter calcoaceticus [8], Desulfovibrio spp. [9,10], Escherichia coli [11], Shewanella spp. [12,13], Pseudomonas spp. [14], Streptomyces sp. [15], in addition to a mixed consortium of sulfate-reducing bacteria [16] also as cyanobacteria [17,18]. Furthermore to entire cells, microbial cell extracts from a number of bacterial species have also been investigated [14]. Apart from these, halophilic bacteria from salt lakes (Halomonadaceae, Bacillaceae, and Idiomarinaceae) had been applied for the production of Pt(0)NPs beneath acidic saline situations (sea salt mixture and NH4 Cl, 20-210 g/L, pH 3-7) [19]. Nonetheless, in spite of the fact that.