Since GPCRs are readily targetable sites for small molecules, as evidenced by their role as drug targets in humans, characterization of GPCRs and related signaling molecules in ES cells may facilitate developing new approaches to ES cell differentiation

sub-lethal concentration of Cry1Ca toxin. Then we measured APN activity levels in Xen-R with and without exposure to Cry1Ca toxin. In agreement with the constitutive midgut activation hypothesis, non-exposed Xen-R…

Interfering with the controlled action of histone methyltransferases by either loss of function or gain of function experiments therefore often results in a deleterious biological outcome due to disturbed proliferation and/or differentiation

To test whether stretch itself directly regulates ERK-dependent h-CaD phosphorylation, we exposed human myometrial strips to in vitro stretch. Human myometrial strips were stretched to Mechanical stretch in vitro increases…

In human breast cancer cells, high levels of palladin expression are associated with increased invasiveness, which suggests the possibility that abnormalities in palladin expression or function might contribute to the disregulated motility of metastatic cancer cells

ray data analysis Cancer module map information was downloaded from the web browser. We used Cancer Module Motif-based profile alignment Chromatin Immunoprecipitation ChIP assays were performed as described with minor…