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The influence of AS-miR-24 on p16 translation was further tested by employing a heterologous reporter system that studies the expression of d2EGFP

mglur mglur April 27, 2017 0 Comments

ed in 131 primary pediatric AML samples with also high expression in t-positive patients. Another study investigated four miRNAs, miR-29a, -155, -196a, and -196b, in 82 pediatric AML samples and…

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The distribution of p16 mRNA was compared between Y and S cells. Unexpectedly, despite the low p16 protein levels in Y cells

mglur mglur April 26, 2017 0 Comments

r attention in future work. For example, Ras may have at least one more effector other than Raf such as PI3K . An adaptor protein, Grb2, one of the key…

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It is known that HESC do express low baseline levels of lineage-specific markers so when differentiation is triggered by EB formation

mglur mglur April 26, 2017 0 Comments

018 0.019 0.019 effluent of neonates with BPD may occur even in the absence of bacterial colonization. The transcriptional activators, NFkB and STAT3, were predicted to be activated by IPA…

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MC631 and TRA-1-60 antibodies were prepared as supernatants of the hybridomas grown in our laboratory as previously described

mglur mglur April 25, 2017 0 Comments

case and exonuclease activities in vitro and in vivo. The level of WRN acetylation increases in cells exposed to methyl methanesulfonate, and long-patch BER activity increases in wild type but…

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we had already lost two-thirds of our SirT1-null mice by the end of this experiment and CR had no obvious beneficial effect on lifespan of these mice

mglur mglur April 25, 2017 0 Comments

e. In the HSF1 promoter, the CGGBP1 binding site could not be site-specifically mutated due to extremely high GC richness and repetitive nature of this region. Instead, we deleted a…

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The dependence on NAD+ as a cofactor for catalysis is thought to link SirT1 activity to the energetic state of the cell

mglur mglur April 24, 2017 0 Comments

ng Measurement Left Ventricular Mass Ejection Fraction Fractional Shortening Normal Diet 15267 7561 4361 High-Fat Diet 13267 7462 4262 Data was obtained from M-mode echocardiographic images taken in parasternal short…

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The two extra residues in the typical 26-residue-long CC-LRRs compared to the 24-residue-long GALA- and GL-LRRs

mglur mglur April 24, 2017 0 Comments

in activity was not affected by Bt-maize either in whole fish or intestinal tract sections during the trial. Amylase activity in PI was significantly increased due to Bt-maize feeding on…

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The fourth aspect of our work relates to the observation that binding between HLA-DRa2 and TIRC7 is functional in T cells HLA-DR Alpha 2 and APC

mglur mglur April 21, 2017 0 Comments

anscriptional repression. This and different knockout phenotypes of NFI genes indicate the 6-Methoxy-2-benzoxazolinone biological activity existence of mechanisms specific for each member. Differential interactions with other proteins, conferred by different…

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As determined by BrdU incorporation, incubation of lymphocytes with sHLA-DRa2 resulted in a concentration-dependent inhibition of proliferation in these proliferation assays

mglur mglur April 21, 2017 0 Comments

a freshly prepared ice-cold buffer suitable for preserving phosphorylation states of enzymes and Western blot was performed, as previously described. Insoluble material was removed by centrifugation for 25 minutes at…

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Quantitative estimates of the secondary structural contributions from CD spectra were made with SELCON 3 using the spectral basis set for membrane proteins implemented in the Olis Global WorksTM software package

mglur mglur April 20, 2017 0 Comments

e expression of orphan nuclear receptor Nur77 and the proapoptotic protein Bim, which are crucial mediators of negative selection, by using the same subsets as used in the above experiment.…

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fucosyltransferase 11 (alpha (1,3) fucosyltransferase)

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fascin actin-bundling protein 1

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