**Background** Protein arginine methyltransferases (PRMTs) play a critical role in regulating gene expression, signal transduction, and DNA repair through the methylation of arginine residues on various proteins. Among these, coactivator…
**Background** The intestinal epithelium serves as a critical barrier between the internal environment of the body and the external lumen, playing a vital role in nutrient absorption and immune defense.…
**Background** Pulmonary fibrosis is a chronic and progressive interstitial lung disease characterized by the excessive accumulation of extracellular matrix proteins, which leads to the destruction of lung architecture and impaired…
**Background** Antibody-drug conjugates (ADCs) represent a sophisticated class of targeted therapeutics designed to combine the high specificity of monoclonal antibodies with the potent cytotoxic effects of small-molecule drugs. The core…
**Background** Hypertension and cardiovascular diseases remain significant global health challenges, often requiring the modulation of calcium influx in vascular smooth muscle cells to reduce blood pressure. Simultaneously, emerging research has…
The fabrication of high-performance separation membranes requires overcoming intrinsic limitations in material stability, defect formation, and interfacial adhesion. Conventional covalent organic framework (COF) membranes often exhibit structural flaws due to…
This study underscores the pivotal role of transparent, primary data in advancing sustainable lithium-ion battery manufacturing, particularly during the early stages of technology development. By conducting a bottom-up energy flow…
The advancement of flexible and wearable optoelectronic devices hinges on the development of transparent conductive electrodes that combine high optical transparency, low sheet resistance, mechanical flexibility, and scalable fabrication. While…
For many women in China, the dream of marriage is a promise of love, family, and stability. But for Tongqi—women who unknowingly married closeted gay men—the reality is far more…
The effective remediation of oil sands process water (OSPW) hinges on the ability to degrade recalcitrant naphthenic acids (NAs), particularly heteroatom-containing variants that contribute significantly to its toxicity. This study…